Effect of technique of surfactant administration (MIST vs. InSurE) on morbidity and mortality profile of preterm neonates treated for RDS: a randomized control trial

Background: Neonatal respiratory distress syndrome is a disease affecting preterm neonates caused by insufficient pulmonary surfactant in alveoli. The reported case fatality rate 57 to 89% low- and middle-income countries. As there very scanty data regarding the studies on MIST technique India, we have generated our institution compare morbidity mortality profile babies with RDS treated InSurE technique. Objective was evaluate effect of administration (MIST vs. InSurE) for RDS. Methods: A Randomised controlled trial, done <34 weeks gestation admitted NICU between January 2020 2021 who required administration. All were fulfilling inclusion criteria after taking informed consent randomized colour coded chits allotted into two groups namely Group (MIST) & B (Conventional- technique). Results: total 100 newborns included study. Among them 50 InSurE. In present study, no statistically significant differences morbity among both study but difference incidence that more group. Conclusions: having similar comparison technique, less than